The research group

We are interested in the role of stem cells in cell turnover in healthy and pathological situations. We study the identity of stem cells and the organization of cellular lineages, the molecular regulation of cell production and the role of cell renewal in homeostasis and pathological situations. Many of our projects focus on stem cells in the brain and spinal cord and adult neurogenesis.

We have recently developed a method for profiling the global expression patterns of RNA in tissue sections called ‘Spatial Transcriptomics.’ We are currently interested in applying this technology to a range of pressing biomedical questions including the spatial organization of stem cells in healthy and diseased tissues and the spatial distribution of immune cells in different cancers and autoimmune lesions.

Description

We are recruiting for a research assistant position in the lab to support ongoing projects in the field of spatial transcriptomics and cancer immunobiology.  The work will be focused on using state of the art sequencing technologies and thus requires a background in both molecular biology and computational biology.  Previous experience working with single cell RNA sequencing and spatial transcriptomic data generation and analysis is required.

Your profile

  1. Bachelor’s Degree or equivalent and having satisfied all course requirements by July 2020.
  2. Fluent written and spoken English.
  3. Prior experience and coursework in computer programming languages (C/C++, R, and/or Python).
  4. The applicant must have substantial experience in laboratory research and in particular with nucleic acids research (PCR, Single Cell RNA sequencing, Illumina library preparation, gene editing/CRISPR). Participation in research that led to research articles published in respected scientific journals is highly recommended.
  5. The position will require preparation of tissues for microscopy and image acquisition and analysis, thus prior experience with advanced microscopic techniques is required.
  6. The applicant should have exhibited a strong track record of leadership and evidence of independent thinking and contributions to research projects in past positions.

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all.

At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Location: Solna

The application is to be submitted through the Varbi recruitment system.

Type of employment Special fixed-term employment
Contract type Full time
First day of employment According to agreement
Salary Monthly salary
Number of positions 1
Full-time equivalent 100%
City Stockholm
County Stockholms län
Country Sweden
Reference number 2-3329/2020
Contact
  • Jeff Mold, Researcher, jeff.mold@ki.se
Union representative
  • Elisabeth Valenzulea,SEKO, 08-524 863 53
  • Magnus Anå, OFR, 08-524 864 37, magnus.ana@ki.se
Published 07.Aug.2020
Last application date 21.Aug.2020 11:59 PM CEST

Return to job vacancies