Research assistant-investigating molecular mechanisms in Childhood Cancer Predisposition and Congenital syndromes - Hiring in process/Finished, not possible to apply

Do you want to contribute to top quality medical research?

Working place

The position is in the Rare Diseases research group. We study genetic disorders on a molecular level in order to understand disease mechanisms and apply new knowledge to genetic diagnostics. We work in a modern laboratory at the Bioclinicum building situated within the grounds of the Karolinska University Hospital, Solna. Several group members also work at the Department of Clinical Genetics at the hospital, the largest clinical genetic department in Sweden with 90 employees working with genetic diagnosis and counseling. We also work closely with the Science for Life Laboratory in Solna, and thus have access to massively parallel DNA sequencing (MPS) with all available technologies. We are currently developing in vitro and in vivo modeling assays to evaluate genetic mutations detected in patients. 

Area of responsibilities/description of the work


We are looking for a motivated person with a background in molecular biology and genetics and an interest to work with bioinformatics.  The selected applicant will help to establish robust techniques to investigate causes behind congenital syndromes and childhood cancer predisposition. The applicant will be involved in WGS panel 30x germline analysis, WGS trio analysis, reanalysis of WGS data, transcriptome analysis and functional studies of new candidate genes and model organisms. 

This project provides the opportunity to participate in a large national translational research project within Genomic Medicine Sweden/Barntumörbanken (GMS/BTB) about Childhood Cancer Predisposition that will have direct clinical impact.

Qualifications

A master degree within the area of biomedical research or corresponding area is required. 
We are seeking a new group member with a broad range of interests and expertise in the following key areas:
1) Knowledge of basic molecular techniques including nucleic acid extraction PCR, qPCR, CRISPR editing, Western blot, immunohistochemistry  
2) Basic and advanced knowledge of cell culture, including fibroblasts, iPSCs and other cell lines
3) Basic programing skills 
4) Good writing skills 
5) Administrative skills

The applicant will be evaluated based on education and previous experience, relevance for the project, track records, motivation, problem solving skills, and cooperative ability. Personal suitability is also an important criterion.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Location:  Solna

Read more: https://ki.se/en/mmk/rare-diseases

Welcome to apply at the latest July 15

The application is to be submitted through the Varbi recruitment system.  

Permanent position is initiated by a six months trial period.

Want to make a difference? Join us and contribute to better health for all