Do you want to contribute to top quality medical research?

We invite applications for a postdoctoral researcher position at the Laboratory of Professor Ernest Arenas (http://ernestarenaslab.org/), in the Karolinska Institute, one of the world’s leading biomedical research universities.

Research group and project

Our lab focuses on defining the cell types, gene expression, gene regulatory networks and function of different cell types during midbrain development as well as in Parkinson’s disease (PD).

Work in this project will focus on developing advanced human iPS models of idiopathic and familial forms of PD, taking in consideration both cell intrinsic and cell extrinsic factors, as well as cell-cell interactions. This project will be complemented by ongoing efforts in our lab to profile and define PD at the single cell level using patient brain tissue samples. Our overall goal is to understand disease mechanisms and develop better disease models and therapies for PD.

Your mission

The successful candidate will have a very strong experience in working with human pluripotent stem cells and performing differentiation into different neural cell types. Experience in single cell RNA-seq, gene editing, bioinformatics, developing iPS-cell-based assays, bioreactors, chemical screens and/or previous work in midbrain development and/or neurodegenerative diseases, such as PD, will be considered as additional merits.

Previous training in a multidisciplinary international environment or outside of the country of origin or in a high profile lab, will be considered as an advantage. The contribution of the applicant to high quality relevant publications will be considered as a merit. The optimal candidate should be a team player, have initiative, be engaged, organized and goal oriented. Good communication skills and proficiency in spoken and written English are required.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Division

The Department of Medical Biochemistry and Biophysics (MBB) has about 300 employees and is organized in divisions covering diverse areas of research. The successful candidate will incorporate to the Division of Molecular Neurobiology, a highly interactive, vibrant and very international young research environment formed by seven research groups and about 70 researchers. English is our common language and we use it in all our activities. Our division works in various aspects of molecular neurobiology and has a unique critical mass contributed by researchers with diverse scientific backgrounds and areas of expertise, including advanced cellular and molecular biology, high content single cell technologies, genetics, epigenetics, bioinformatics, biochemistry, electrophysiology, behavior, imaging, developmental neurobiology, cellular reprogramming and stem cell biology.


Location:
Solna, Biomedicum

Application

Applications must contain the following documents in English or Swedish:

  • A complete curriculum vitae, including date of the thesis defense, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)
  • A personal letter with motivation
  • The name, e-mail and phone of two recent group leaders to provide reference letters

Want to make a difference? Join us and contribute to better health for all

Type of employment Temporary position longer than 6 months
Contract type Full time
First day of employment Upon agreement
Salary Monthly
Number of positions 1
Working hours 100 %
City Solna
County Stockholms län
Country Sweden
Reference number 2-590/2020
Contact
  • Ernest Arenas, +46 (0)8-524 876 63
Published 03.Feb.2020
Last application date 01.Mar.2020 11:59 PM CET

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