Karolinska Institutet, Department of Medical Biochemistry and Biophysics, Translational Medicine and Chemical Biology

For our growing interdisciplinary and multi-national team, we are recruiting a postdoctoral researcher (ERC-funded 2 year scholarship position in first instance, up to 5 years).  To unravel the molecular circuits that underlie epigenetic gene regulation and inheritance, my laboratory aims to increase the spatiotemporal resolution and biochemical precision of methods for studying chromatin in living cells. In an interdisciplinary team, we will be developing tools to engineer proteins in living cells based on genetic code expansion and unnatural amino acid mutagenesis. We will, for example, control and probe chromatin proteins using light-activated and bioorthogonal chemistries. These methods, combined with quantitative, high-throughput, proteomic and genomic read-outs, will allow us to dissect the complex mechanisms governing chromatin dynamics, histone modifications and epigenetic inheritance. For more information and latest news visit http://elsaesserlab.org.

Requirements
Applicants should hold a doctoral degree or expect to defend in 2016. Excellent education and laboratory skills in molecular biology are a prerequisite.

The ideal candidate has one of the following profiles:

  1. extensive experience in ChIP-Seq, ATAC-Seq, DHS, or related methodologies, including cell and sample preparation, next-generation sequencing library preparation; experience in data analysis using third-party software and scripting languages.
  2. extensive experience in R, Python, MatLab or related programming languages for the analysis of next-generation sequencing data and basic experience in wet lab techniques such as library preparation.
  3. extensive experience in Mass Spectrometry and Proteomics, including cell and sample preparation, operation and maintenance of LC-MS/MS systems, data analysis.

The candidate should be enthusiastic, motivated, result-driven, and creative minded, with good organization, writing and communication skills. The candidate should be interested in fundamental research questions and be able to work well both independently and in a team environment.

Type of scholarship
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent. This educational scholarship is tax-exempt.

Application process
An application must contain the following documents in English:

  • A personal letter and curriculum vitae: include details on your education and average grade for Bachelor and Masters degrees.
  • A list of degree projects and any previous publications
  • Contact details for three referees 

The application is to be submitted on the MyNetwork recruitment system.
Karolinska

Type of employment Postdoctoral scholarship
Contract type Full time
Number of positions 1
Working hours 100 %
City Stockholm/Solna
County Stockholms län
Country Sweden
Reference number 2-3592/2016
Contact
  • Simon Elsässer, +46 (0)8-524 800 00
Union representative
  • Henry Wölling, SEKO, +46 (0)8-524 840 80
  • Biborka Bereczky Veress, SACO, +46 (0)70-173 85 75
  • Anne Edgren, OFR/S, P, O, +46 (0)8-616 16 29
Published 03.Jan.2017
Last application date 31.Jan.2017 11:59 PM CET

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