Karolinska Institutet, Department of Medical Biochemistry and Biophysics, Translational Medicine and Chemical Biology

For our growing interdisciplinary and multi-national team, we are recruiting a PhD student on an ERC funded (4-year) position.

To unravel the molecular circuits that underlie epigenetic gene regulation and inheritance, the laboratory aims to increase the spatiotemporal resolution and biochemical precision of methods for studying chromatin in living cells. In an interdisciplinary team, we will be developing tools to engineer proteins in living cells based on genetic code expansion and unnatural amino acid mutagenesis. We will, for example, control and probe chromatin proteins using light-activated and bioorthogonal chemistries. These methods, combined with quantitative, high-throughput, proteomic and genomic read-outs, will allow us to dissect the complex mechanisms governing chromatin dynamics, histone modifications and epigenetic inheritance. For more information and latest news visit http://elsaesserlab.org

Applicants should hold a masters' degree or equivalent in biochemistry, chemistry, bioinformatics or life sciences. Excellent education and laboratory skills in molecular biology are a prerequisite. Experience in at least one of the areas of mammalian tissue culture, genomics, next-generation sequencing, advanced light microscopy are expected.

The candidate should be enthusiastic, motivated, result-driven, and creative minded, with good organization, writing and communication skills. The student should be interested in fundamental research questions and be able to work well both independently and in a team Environment.

We are located at the modern Science for Life Laboratory (SciLifeLab) in Stockholm, Sweden. SciLifeLab also houses numerous state-of-the art national core facilities. We are part of the Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics. Karolinska Institutet ranks as one of the world’s leading medical universities.

Application process
An application must contain the following documents in English:

  • A personal letter and curriculum vitae: include details on your education and average grade for school leaving qualification (e.g. high school diploma, A-level, Abitur, Matura), Bachelor and Masters degrees. Explain grading system or give percentile rank of your grade in your class/year.
  • A list of degree projects and any previous publications (do not attach copies of reports or publications)
  • Contact details for two referees (mentors that can judge your practical or course work)
  • Do NOT attach reprints of papers or thesis documents to your CV

The application is to be submitted through the MyNetwork recruitment system.

The fine print
A doctoral position is an available doctoral education project to which a PhD student is to be recruited. After the selection process the process for admission to doctoral education will commence. An admission decision will not be taken until the departmental admission board has approved an individual study plan.

During the time between recruitment and admission a short-term employment can be offered for up to 6 months.

For more information regarding doctoral (PhD) education, see: http://www.ki.se/doctoral

Entry requirements for doctoral education at KI
A person meets the general entry requirements for doctoral/third-cycle/PhD education (according to Higher Education Ordinance Chapt 7, section 39) if he/she:

  1. has been awarded advanced/second-cycle/master qualification (i.e. master degree) or
  2. has satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the second-cycle/master level, or
  3. has acquired substantially equivalent knowledge in some other way in Sweden or abroad.

Specific entry requirements
Proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school:
Proficiency in the English language can be documented by an internationally recognized test such as TOEFL or IELTS, see web-link below for more information.
Applicants who meet the general entry requirements (1 or 2 above) from a university in one of the Nordic countries fulfill the requirements in English.

For more information regarding general and specific entry requirements: http://ki.se/en/education/entry-requirements-eligibility-for-doctoral-education

Assessment criteria
A selection will be made among qualified applicants on the basis of the ability to benefit from doctoral education. Karolinska Institutet uses the following bases of assessment:

  • Documented subject knowledge of relevance to the area of research
  • Analytical skill
  • Other documented knowledge or experience that may be relevant to doctoral studies in the subject

The qualifications of the applicants will be evaluated on an overall basis.

Type of employment PhD placement
Contract type Full time
Reference number 2-3484/2016
  • Simon Elsässer, +46 0(8)-524 800 00
Union representative
  • Biborka Bereczky Veress, SACO, +46 (0)70-173 85 75
  • Anne Edgren, OFR/S, P, O, +46 (0)8-616 16 29
  • Henry Wölling, SEKO, +46 (0)8-524 840 80
Published 16.Sep.2016
Last application date 31.Oct.2016 11:59 PM CET

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