Postdoctoral studies in translational cell- and gene therapy

Do you want to contribute to top quality medical research? 

Division of Biomolecular and Cellular Medicine (BCM)

Activities at the Division of Biomolecular and Cellular Medicine (BCM) focus on the application of modified biomolecules, cells and cell products as novel therapy agents as well as the identification and study of appropriate biomolecular and cellular targets for therapy and diagnosis.

You will be affiliated to the Research group of Professor Stephan Mielke:

“Our team works with translational questions between basic research and clinical care in the field of cell- and gene therapy with a strong focus on cancer.”

Duties

You will be working as part of our translational team will all questions of translational cell- and gene therapy.

Your main task is going to work the regulatory translation of in vivo CD19 CAR-T cells into a phase 1 first in man first in human clinical trial. You will coordinate all the translational efforts and work closely with the research teams, the clinicians, the clean-room team, the CRO and the regulators.

 One of your other tasks will be on ovarian cancer and the collection and analysis of human samples. This will include several techniques, mainly but not exclusively in the wet lab such FACS, histology, PCR, single cell sequencing, whole genome sequencing, cell culturing, killing assays etc. Your will work closely to our clinical teams. The goal is to establish a hospital-based production platform for a cellular therapeutic against ovarian cancer.

Entry requirements

Postdoctoral scholarships may be established for foreign researchers who pursue their merit in Sweden. A foreign researcher is a person living in another country who comes to Sweden with the intention of only staying in Sweden for all or part of their postdoctoral education at KI. Persons who are resident in Sweden and/or have carried out all or part of their academic education at KI or some other educational institution in Sweden cannot be considered for scholarships. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.

A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four-year period following the receipt of a doctoral degree or equivalent.

To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate, or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post-doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

For this position a medical background in either human or veterinary medicine as well as previous translational experience with cellular products/ATMPs is required.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Students and employees have free access to our modern gym facilities with trained staff on site.

Location: You will be working at Karolinska Institutet in Huddinge/Campus Flemingsberg.

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.

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