Postdoctoral studies in the field of molecular aging (Scholarship) - Hiring in process/Finished, not possible to apply

Do you want to contribute to top quality medical research?

The research group of Professor Maria Eriksson at the department of Biosciences and Nutrition is looking for a highly motivated postdoctoral researcher to study somatic mutations in age-associated disease. The research group use both patient material and animal models combined with modern genomic technologies that allow for detailed analysis down to single-cell resolution to try to answer disease-relevant fundamental questions. https://ki.se/en/bionut/genetic-mechanisms-of-ageing-maria-eriksson

Division

The research group of Professor Maria Eriksson aims to identify novel genetic mechanisms of aging with a special focus on somatic mutations and their functional contribution to aging and age-associated diseases. The group also has a long-standing interest in the study of the premature aging disorder Hutchinson-Gilford progeria syndrome, trying to identify novel targets for treatment. The group consists of 2 postdocs and 2 PhD students, and is looking to expand with 1 additional postdoc.

The research group is part of a larger “Aging and Cancer” space that consists of 6 other research groups located next to each other within Neo, a modern research building. Such stimulating environment allows for several arrangements of joint events and promotes daily interactions, collaborations and sharing of expertise.

Duties

Somatic cells accumulate thousands of mutations during development and aging. However, detailed analysis and insight into the extent of somatic variance in the vascular tissue is lacking. The postdoc will study the clonality of the vascular wall in human tissue samples and generate advanced mouse models based on lineage tracing to follow the fate of mutated cells. The aim is to define functional implications of somatic mutations in relation to aging and age-associated cardiovascular disease. The research work includes standard molecular biological techniques, mouse phenotyping and modern omics-approaches. The postdoc is expected to be part of the group and to develop in accordance with the common group goals and research interests.

Applications are invited from highly motivated individuals with a PhD and a strong background in molecular biology or genetics. Previous extensive experience from work with mouse models and tissue functional tests is required. Experience from work on the vascular system and lineage tracing, using confetti or similar strains, and rare event detection, is advantageous. The successful candidate is enthusiastic, responsible, able to plan and perform own experiments and analysis. The candidate should be able to function well in the group and be able to provide suggestions and support in experimental design and experimentation to other members of the group. Fluency in written and spoken English is a requirement.

Entry requirements

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Location: Flemingsberg

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.

https://ki.se/en/bionut/genetic-mechanisms-of-ageing-maria-eriksson

https://ki.se/en/bionut/department-of-biosciences-and-nutrition

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