Post-doctoral researcher in Biomaterials and Regenerative Medicine

Do you want to contribute to top quality medical research?

Karolinska Institutet, Department of Medical Biochemistry and Biophysics, Division of Biomaterials

A post-doctoral researcher position is available in the group of Professor Molly Stevens in the Division of Biomaterials at the Department of Medical Biochemistry and Biophysics (MBB). The successful applicant will join a multidisciplinary research team with a translational profile in biomaterials and tissue engineering, and should have expertise in developing and characterizing novel lipid nanoparticle formulations for healthcare applications.

The successful candidate will be involved in contributing to translational projects at the interface between biomaterials science, chemistry and biology. The candidate will work on the development and characterization of composite materials with controlled architecture, composition and biological activity of a range of healthcare applications. Focus of the research will be in the field of soft matter applications for healthcare. In particular, the role entails the design, preparation and characterization of a range of lipid nanoparticle formulations for drug delivery applications. The candidate will be offered extensive opportunities for collaborative work, both within KI and external to the group of Molly Stevens at Imperial College in London and other academic research groups as well as industrial partners.

Your mission

Key Responsibilities:

To conduct multidisciplinary projects by using supramolecular chemistry to develop novel lipid nanoparticle formulations, and to explore these formulations and their potential applications for healthcare.
To plan and execute laboratory experiments independently and in close collaboration with other researchers and industrial collaborators.
To undertake the associated data analysis and interpretation of data.
To help the other research staff in the daily management of the group laboratories (organizing group networking events, laboratory cleaning and organization, supervision of visiting students etc.)
To write progress reports and prepare results for publication and dissemination via journals, presentations and the web.
To promote translational research by contributing to IP application preparation when applicable.
To attend group meetings, project and progress and meetings, national/international seminars and conferences, and network with the other researchers.

Experience and Knowledge:

Strong background in supramolecular chemistry [ESSENTIAL]
Experience in self-assembly and host-guest chemistry [ESSEANTIAL]
Experience in 1D and 2D NMR techniques, e.g. COSY, NOESY, DOSY, etc… [ESSENTIAL]
Experience in lipid nanoparticle formulation, fabrication, and characterization [DESIRABLE]
Experience in DLS [ESSENTIAL]
Experience in using microfluidics for lipid nanoparticle fabrication [ESSENTIAL]
Experience in applying for research grants [ESSENTIAL]
Experience in collecting and analysing small angle X-ray scattering (SAXS) data Experience in writing and submitting SAXS beamtime proposals
Experience and/or willingness to receive additional training in in vitro cell culture
Experience and/or willingness to receive training in other nanomaterials characterization techniques including, cryo-TEM, NTA, SANS, etc…

Skills and Abilities:

Excellent written and oral communication skills in English
Demonstrable ability for innovation and original research
A proven record of publications in top journals
Demonstrated ability to work in a collaborative and multidisciplinary environment
Experience in mentoring students
Demonstrated ability to collaborate with academics from different disciplines
A creative approach to problem-solving

Your profile

Qualified to be employed as a post-doctoral researcher is one who has obtained a doctorate and has previous post-doctoral experience in chemistry, biomaterials, or other relevant discipline. More specifically, this role also requires experience in i) supramolecular chemistry, particularly in self-assembly and host-guest chemistry, ii) application of these principles to lipid nanoparticle formulation and fabrication, iii) optimization of the fabrication of novel lipid nanoparticles using microfluidics, iv) characterization of novel lipid nanoparticles using DLS and SAXS. Also required are v) a strong track record of conducting research projects including mentoring students and successful grant applications, vi) a strong track record of organizing networking events, conferences, and workshops. Excellent communication and organizational skills are necessary. A proven record of publications in top journals is essential.

A person is eligible for a position as post-doctoral researcher if he or she has obtained a PhD no more than seven years before the last date of employment as post-doctoral researcher.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work A complete list of publications A summary of current work (no more than one page)

Welcome to apply at the latest 2022-05-24

The application is to be submitted through the Varbi recruitment system.

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