Karolinska Institutet, Department of Medicine, Solna, Cardiology division

The Department of Medicine, Solna, is one of the largest departments at Karolinska Institutet. The department consists of several divisions that are separated into different research groups. The core activities of the department are research, doctoral education and undergraduate education for medical and biomedical students. The research has three main profiles: allergy, cardiovascular medicine and inflammatory diseases.

Division
The research group is located at Cardiology Unit, Department of Medicine, Solna. The group consists of a team of physicians and scientists focused on studying the molecular and cellular processes underpinning vascular and cardiac dysfunction in the context of diabetes. Key aspects of the research program also include the link between environmental factors, metabolic disease and premature cardiovascular ageing. These objectives are accomplished by a translational approach aimed to characterize cardiovascular disease phenotypes through novel technologies, genetically-engineered animal models and human studies.

Duties
The position focuses on the molecular and cellular processes underlying vascular and cardiac dysfunction in the context of obesity, diabetes and associated metabolic disease. A major part of the project will be to identify detrimental epigenetic signatures eliciting oxidative and inflammatory changes.

Entry requirements
Applicants must hold a PhD in Biomedicine (or an equivalent scientific degree), be highly motivated, independent and senior enough to organise the work of biological or medical doctoral students and integrate themselves into a team. An excellent background in molecular biology with a strong track-record in microparticles, extracellular vescicles, non-coding and microRNAs studies, ChIP assay and gene profiling of chromatin modifying enzymes is required. Experience on identification of candidate differential miRNAs by Affymetrrix Gene Chip miRNA array system and the validation of miRNA signatures by Custom TaqMAn miRNA Card is necessary. Previous experience in basic and translational studies on atherothrombosis research is an advantage.The candidate will work in an international and highly motivated surrounding. Proficiency in English, both spoken and written and basic knowledge of Swedish are mandatory.

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence.

Application process
An employment application must contain the following documents in English or Swedish:

  1. A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  2. A complete list of publications
  3. A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system.

Type of employment Tidsbegrænset ansættelse mere end 6 måneder
Contract type Full time
Number of positions 1
Working hours 100&
City Solna
County Stockholms län
Country Sweden
Reference number 2-2694/2019
Contact
  • Francesco Cosentino , 08-517 75 398
Union representative
  • Biborka Bereczky Veress, SACO, 46 70-173 85 75
  • Niklas Andersson, OFR, niklas.andersson@ki.se
Published 06.May.2019
Last application date 16.May.2019 11:59 PM CET

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