Postdoctoral researcher in Bioinformatics

Do you want to contribute to top quality medical research?

We are looking for an ambitious PhD graduate with skills in bioinformatics and/or epigenomics to perform cutting-edge research in the Laboratory of Chemical and Synthetic Systems Biology. We offer an engaging and international research environment and the opportunity to contribute to high-quality research on an internationally competitive level. We are looking for a highly motivated individual, who excelled during her/his doctoral studies, has computational experience, and strong documented interest in epigenetics in particular.

The research group

The Elsässer group is an international and multicultural research group that focuses on applying new synthetic and chemical biology methods to understand chromatin structure and function. We are a dynamic, collaborative, and supportive team within the Division of Genome Biology, Department of Medical Biochemistry and Biophysics located at the Science for Life Laboratory in Stockholm. The group includes senior and junior researchers, bioinformaticians, administrators, PhD students and undergraduate trainees.

Your mission

To unravel the molecular circuits that underlie epigenetic gene regulation and inheritance, my laboratory combines chemical and synthetic biology manipulation of living cells with systems-level (genomic and proteomic) readouts. The successful candidate will thus participate in the processing, analysis, integration and publication of next- generation sequencing (NGS) data including quantitative ChIP-Seq, RNA-Seq, TT-Seq, chromosome interactome data and proteomics. The tasks will include statistical analysis, meta-analysis and data modeling. The successful candidate will work together with other members of the team and with collaborators. The ability to work independently and as part of a team is essential for this position. For more information and latest news visit http://elsaesserlab.org

Your profile

To be eligible for employment as a postdoctor a phd or a foreign degree deemed to be equivalent to a Swedish phd is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

A doctoral degree, or a foreign degree deemed to be equivalent to a doctoral degree no earlier than 2023 within bioinformatics and computational biology.

Required skills of the successful candidate are:

• firm knowledge in R, Unix/Linux, Perl, Python
• robust mathematical and statistical background knowledge
• experience in the analysis of next-generation sequencing data
• experience in pipeline development and data management
• knowledge of relevant biological areas (chromatin and gene expression, genetics and epigenetics)
• experience in MatLab, Mathematica or related programming languages is an advantage
• knowledge in biostatistics
• experience in data genomics data mining and visualization
• proficiency in written and spoken English
• experience in publishing software (provide a link to your GitHub repository)

It is a merit if the applicant can document the following:

• Understanding of biological concepts and/or willingness to learn. Experience in working with wet lab scientists is a plus
• Excellent organizational, communication and social skills
• Excellent presentation skills

The bioinformatician will work closely with the main supervisor, Dr. Simon Elsässer, wet lab students and postdocs that generate the data. 

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: SciLifeLab, Solna

Application

An employment application must contain the following documents in English or Swedish:

• PhD certificate
• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

Welcome to apply at the latest 2025-01-01

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all!