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Karolinska Institutet, Department of Oncology-Pathology, Lehtiö research group
At the Department of Oncology-Pathology basic, translational and clinical research and educational activities related to cancer is carried out. Approximately 300 people from over 40 nations are currently working at the department. About 30 research groups with various cancer research profiles are involved and we have around 110 PhD students. The Department of Oncology-Pathology is responsible for undergraduate courses in Pathology, Oncology and Forensic Medicine for medical students, as well as for Tumor biology courses for biomedicine students and Pathology courses for opticians.
The bioinformatics work will be conducted in the Cancer proteomics Mass spectrometry research group headed by Professor Janne Lehtiö at Science for Life Laboratory (SciLifeLab). Karolinska Institutet is one of the four founding universities for SciLifeLab which is today a national infrastructure and research center in technology driven life sciences. Lehtiö group is a translational group of scientists with a drive to improve human proteome analysis by developing and using new proteomics methods that can be applied to improve personalized cancer treatment. We now need to strengthen our leukemia sub-group with a bioinformatician within the field of multi-omics data analysis and cancer research. We offer a very stimulating and diverse working atmosphere in a team of very motivated cancer researchers.
We are looking for an outstanding candidate with focus on bioinformatics and experience in omics data analysis. The position requires solid expertise in genomics, transcriptomics and/or proteomics data analysis and communication skills and willingness to work in a team environment. The current position offers great possibility for innovative research combining proteomics and genomics data, together with a dedicated group of scientists.
The bioinformatician will work on integrative and translational analysis of multiple levels of omics data derived from various lymphoid malignancies such as AML and ALL cell lines as well as clinical specimens with the aim of identifying novel therapeutic and resistance biomarkers. The focus will be on developing and applying ‘omics’ methods on biologically/clinically oriented research questions and to analyze the acquired data as well as to validate the findings using public domain data. This includes both applying established data analysis steps as well as investigating new strategies and solutions for the analysis of quantitative biological data.
Important components of the work are experimental design, development of proteomics/ genomics/transcriptomics pipelines and statistical analyses of quantitative data and development of software and tools for data visualizations. It is expected that the applicant is well acquainted with software and programming languages related to omics data analysis. The candidate is expected to take a strong lead in managing and driving the project(s) as well as writing manuscripts.
Tasks for the position:
Qualifications
Additional merits
Since the position involves close interaction with several researchers, emphasis is placed on personal skills such as:
A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.
Location: Science for Life Laboratory in Solna
Choose to work at KI – Ten reasons why
Lehtiö Lab (lehtiolab.github.io)
Welcome to apply at the latest 5th March.
The application is to be submitted through the Varbi recruitment system.In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form.
Permanent position is initiated by a six months trial period.
Type of employment | Permanent position – (starting with a temporary contract) |
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Contract type | Full time |
First day of employment | 1 June, Up on agreement |
Salary | Monthly salary |
Number of positions | 1 |
Full-time equivalent | 100 % |
City | Solna |
County | Stockholms län |
Country | Sweden |
Reference number | STÖD 2-836/2024 |
Contact |
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Union representative |
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Published | 20.Feb.2024 |
Last application date | 05.Mar.2024 11:59 PM CET |