Postdoctoral studies in translational studies in malignant melanoma

Do you want to contribute to improving human health?

At the Department of Oncology-Pathology basic, translational and clinical research and educational activities related to cancer is carried out. Approximately 300 people from over 40 nations are currently working at the department. About 30 research groups with various cancer research profiles are involved and we have around 110 PhD students. The Department of Oncology-Pathology is responsible for undergraduate courses in Pathology, Oncology and Forensic Medicine for medical students, as well as for Tumor biology courses for biomedicine students and Pathology courses for opticians.

The Childhood Cancer Research Unit is one of the leading international centres for translational research in paediatric oncology.

The outcome in metastatic melanoma has dramatically improved by the introduction of targeted and immune-based therapies. Treatment predictive biomarkers and novel therapeutic strategies in sub-groups patients are warranted. The team led by Associate professor Hanna Eriksson (MD, PhD) is focusing on clinical and translational melanoma research. The team led by Assistant professor Nikolas Herold (MD, PhD) is focusing on translational research of immunotherapy and chemotherapy resistance. Both teams have joined forces for this collaborative project.

Hanna Eriksson Research Team and Department of Women’s and Children’s Health, Childhood Cancer Research Unit, Nikolas Herold Research Team

Your mission

We are looking for a postdoc who is curious and eager to solve biological questions with focus on translational omics research.

The current position offers outstanding opportunities to develop as a researcher in an innovative and stimulating research environment together with a dedicated group of scientists and clinicians where the postdoc will contribute with their expertise.

The postdoc will work on clinical specimens from melanoma patients as well as with cell lines and mouse models with the aim of identifying novel therapeutic targets and treatment predictive biomarkers. The research project is therefore performed in close collaboration between the clinic and Karolinska Institutet. The focus will be on applying gene expression models on biologically/clinically oriented research questions and to analyze the acquired data as well as to validate the findings using public domain data. This includes cell- and molecular wet-lab experimental methods as well as investigating new strategies and solutions for the developing these methods.

Your profile

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent. A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent. The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable
Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

Qualifications

• PhD in biology, medicine, biomedicine, or another relevant field.

• Documented experience in of cell- and molecular wet-lab experimental methods including experience in MS proteomics, NGS, extracellular vesicle analyses, other high-throughput / high-dimensionality generating methods.

• Knowledge of systems biology/systems medicine, large-scale data analysis, integration and visualization.

• Knowledge in statistical methods.

• Ability to interpret omics data in a biological context.

• Excellent communication and team work skills

• Fluent in English language.

Additional merits

Since the position involves close interaction with several researchers, emphasis is placed on personal skills such as:

• Very good collaborative skills

• Excellent communication skills and analytical skills

• Curious and eager to solve biological questions

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
A complete list of publications
A summary of current work (no more than one page)

Welcome to apply at the latest xxx

The application is to be submitted through the Varbi recruitment system.

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