Do you want to contribute to top-quality biomedical research?

A Lab Manager position is immediately available in the Bienko and Crosetto labs for Quantitative Genome Biology at the Science for Life Laboratory (SciLifeLab) in Stockholm. We are searching for an organized, skilled, and highly motivated Lab Manager who will overlook our lab efforts and secure smooth functioning of the lab.

Your mission

Main tasks will include standardization of protocols, supervision of cell culture work, cultivation of cell lines, preparation of microscopy samples, common reagents, and libraries of fluorescent in situ hybridization probes. Furthermore, the Lab Manager will be responsible for lab safety compliance and ordering of reagents.

Specifically, your tasks will include:

--Culturing mammalian cells and processing them in preparation for different sequencing and FISH assays

--Performing GPSeq (Nat Biotechnol 2020) and iFISH (Nat Commun 2019) in the frame of various collaborative projects

--Setting up CRISPR technology in our lab

--Performing immunostaining, western blotting and/or PCR (occasionally)

--Extracting nucleic acids from clinical samples (occasionally)

Your profile

The successful candidate will have managerial responsibilities such as training newcomers in basic cell biology and molecular biology techniques, as well as on microscope use, and will be responsible for making sure that our databases as well as protocols are up to date.

The Lab Manager should be capable of working independently and be proactive in the implementation of procedural improvements to ensure that the lab runs safely and efficiently. Hence, we are searching for a highly energetic person with a great deal of independence and initiative, with passion for experimentation and great communication skills.

Requirements:

In order to be eligible for this position, you must hold a PhD degree in Biology, Bioengineering, Biomedicine, Medicine or equivalent, and have worked for at least one year as a lab manager. Prior experience with DNA and/or RNA FISH is a plus.

The research groups

The position is available in the Bienko and Crosetto laboratories for Quantitative Biology and Technology (https://bienkocrosettolabs.org/). The Bienko and Crosetto labs are located at the Science for Life Laboratory (SciLifeLab) situated at the Karolinska Institutet Solna campus.

The Bienko lab explores the fundamental design principles that regulate how chromatin is organized in the eukaryotic nucleus in normal and disease conditions, and how the 3D chromosome structure influences gene expression.

The Crosetto lab investigates the molecular basis of DNA fragility and tries to understand how the interplay between DNA replication and transcription is linked to the formation of DNA breaks genome-wide.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Location: Solna, SciLifeLab

Application

An employment application must contain the following documents in English:

  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)
  • Verification from the thesis defence committee or the equivalent (only if the thesis defence is scheduled within three months after the application deadline)

Welcome to apply at the latest 30th of June 2020. 

The application is to be submitted through the Varbi recruitment system.  

Permanent position is initiated by a six months trial period.

Want to make a difference? Join us and contribute to better health for all

Type of employment Temporary position
Contract type Full time
First day of employment Immediately/as soon as possible
Salary Monthly salary
Number of positions 1
Full-time equivalent 100 %
City Stockholm
County Stockholms län
Country Sweden
Reference number 2-2755/2020
Contact
  • Nicola Crosetto, +46 (0)733 48 40 40
Published 16.Jun.2020
Last application date 30.Jun.2020 11:59 PM CEST

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