Karolinska Institutet, Department of Oncology-Pathology, Forskargrupp Kallioniemi

At the Department of Oncology-Pathology basic, translational and clinical research and educational activities related to cancer is carried out. Approximately 300 people from over 40 nations are currently working at the department. About 30 research groups with various cancer research profiles are involved and we have around 110 PhD students. The Department of Oncology-Pathology is responsible for undergraduate courses in Pathology, Oncology and Forensic Medicine for medical students, as well as for Tumor biology courses for biomedicine students and Pathology courses for opticians.

Research group Olli Kallioniemi
This position resides in the research group of Olli Kallioniemi, Director of Science for Life Laboratory, Professor of Molecular Precision Medicine, affiliated with both the Dept. Oncology and Pathology, Karolinska Institutet and the Science for Life Laboratory. The work will involve an exciting opportunity to practice precision cancer medicine research in a translational setting, with the aim to assign and optimize targeted treatments for individual cancer patients. Our disease focus is on acute myeloid leukemia (AML), ovarian and urological tumors (prostate, kidney and bladder). Our goal is to develop a systems biology framework to match targeted therapies and drug combinations using genomic, transcriptomic and proteomic profiling along with functional ex vivo drug testing on primary patient-derived cells (PDC) from cancer patients. We work through team science in close collaboration not only with other research groups, but also with clinicians, as well as with different technology platforms of the SciLifeLab. For more information : https://www.scilifelab.se/researchers/olli-kallioniemi/ 

Task Description
The tasks for this position involves the establishment of innovative drug testing assays in primary cell models, characterization of the models and integration of the datasets to inform patient treatment. The candidate is also expected to carry out project management tasks such as carrying out expected milestones within the project, budgeting and reporting as well as interacting not only with research but also clinical and pharma collaborators.

Qualifications
The successful candidate is expected to have a doctoral degree in biochemistry, biology, biotechnology, medicine or other relevant field. The candidate, is independent and motivated with a documented ability to carry out experimental research projects but also project management including excellent communication skills in spoken and written English. Previous expertize in primary model development from solid tumors and/or hematological cancers is beneficial. Experience with high throughput drug testing, assay development, high throughput high content microscopy and –omics technologies is highly valued. We stress research expertise and interest in collaborative science when assessing applicants.

Requirements:
- PhD in biochemistry, biology or medicine.
- Knowledge of cancer biology, precision cancer medicine and translational cancer research.
- Extensive experience in cell culture techniques, especially primary cell models. 
- Knowledge on high-throughput drug testing and assay development
- Experience in working as part of large multidisciplinary, collaborative research projects (“team science”).

Application process, salary and contract
An application must contain the following documents in English: Curriculum vitae, qualifications and description of planned research, presented in accordance with Karolinska Institutet’s qualifications portfolio. For more information: http://ki.se/qualificationsportfolio.

The application is to be submitted through the MyNetwork recruitment system. The salary is defined according to the KI salary system. The project is initially for one year contract with the possibility of extension with the preferred start date as soon as possible.

Type of employment 临时职位(6个月以上)
Contract type Full time
Number of positions 1
Working hours 100%
City Solna
County Stockholms län
Country Sweden
Reference number 2-4544/2019
Contact
  • Päivi Östling, paivi.ostling@ki.se, +46 (0)73 673 5762
Union representative
  • Andreas Lundqvist, SACO, 46 8 517 76884
  • Helen Eriksson, OFR, 08 517 762 79
Published 10.Sep.2019
Last application date 10.Nov.2019 11:59 PM CET

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