Karolinska Institutet, Institutionen för biovetenskaper och näringslära, Strömberg (RST)

The Department of Biosciences and Nutrition performs research and education in several areas of medical science including bioorganic chemistry, molecular endocrinology, cancer biology, functional genomics, systems biology, epigenetics, structural biochemistry, cellular virology, and nutrition. It offers an excellent international research and working environment, including around 300 scientists, students, administrative and technical personnel. The Department resides in the new biomedical research building Neo, aimed at being a creative and open environment that enables meetings, synergies, and exploration of areas of mutual interest across disciplines.

Description of research group and project
We are looking for a senior Researcher to Professor Roger Strömberg´s group. https://ki.se/en/bionut/unit-for-organic-and-bioorganic-chemistryThe group consists of a Senior Lab Manager, PhD students and Senior Researchers

The research group focuses on development of modified oligonucleotides and peptides, their conjugates, and different ligands for either of these biomolecules. Oligonucleotides are designed to have specific properties for potentiation and development of therapeutic approaches, e.g., in oligonucleotide therapy.

Duties
The work includes (i) development of synthesis methods for the preparation of modified nucleosides, nucleotides, oligonucleotides and conjugates, linkers, amino acids, peptides and conjugates (ii) synthesis of novel oligonucleotides and conjugates that promote cellular uptake, nuclear localisation and/or organ targeting. Teaching of undergraduate students is a part of the responsibility as well as supervision of post-docs and PhD students.

The position is for one year to begin with.

Entry requirements
A person is eligible to be appointed Senior Researcher if he or she has been awarded a Degree of Doctor or has achieved the corresponding scientific competence, as well as documented research after publicly defending his or her doctoral thesis corresponding to qualification as Assistant professor.

In connection with the appointment, we will accord special weight to academic skills, particularly demonstrated excellence in research including a significant track record and interdisciplinary research experience.

Qualifications
We are looking for a highly motivated researcher with a PhD and post-doctoral experience in Organic chemistry with specialization in Nucleic Acids chemistry and Peptide chemistry. The successful candidate must have a strong background in the state-of-the-art synthesis of nucleosides, nucleotides, oligonucleotides, amino acids, and peptides including their modifications (both pre and post) and conjugates. It is expected that the successful candidate also has experience in work with ligands binding to peptides and techniques such as NMR, UV, fluorescence and CD spectroscopy analysis of oligonucleotides and peptides.

Capability to propose a high-level research plan will be essential. Working in an international research group engaged in multiple collaborations, the successful candidate must be a team worker with excellent written and verbal communication skills (in English)

The position involves teaching activities in the areas of bioorganic and food chemistry as well as laboratory supervision of graduate students, post-graduate students and postdoctoral fellows. It is then also preferred that the candidate has taken some pedagogic course for university teachers.

Bases of assessment
We stress research expertise when assessing applicants. Emphazis will be placed on personal suitability.

Application process
An application must contain the following documents in English:
- A complete vitae, including qualifications and description of planned research
- Letter of interest

The application is to be submitted through the Varbi recruitment system.  

Type of employment Temporary position
Contract type Full time
Number of positions 1
Full-time equivalent 100 %
City Huddinge
County Stockholms län
Country Sweden
Reference number 2-2816/2018
Contact
  • Roger Strömberg, Professor, +46-8-524 810 24
  • Thomas Tinglöv, Head of Administration, +46-8-524 835 49
Union representative
  • Henry Wölling, SEKO, +46-8-524 840 80
  • Birgitta Lindqvist, OFR, +46-8-524 810 28
Published 21.May.2018
Last application date 05.Jun.2018 11:59 PM CEST

Return to job vacancies